By Karen Herzog of the Journal Sentinel – June 10, 2014 –
The first national study to focus on prevention of memory loss associated with Alzheimer’s disease is seeking older Wisconsin residents with normal memory and thinking abilities to be part of a clinical trial through the University of Wisconsin-Madison School of Medicine and Public Health.
The goal of the three-year study with clinical trials at over 50 sites around the nation is to see whether a medication can help slow or stop the onset of Alzheimer’s in people at risk.
Early detection of Alzheimer’s is a major focus at UW-Madison’s Alzheimer’s Disease Research Center, so the site will be enrolling more participants than the average site around the country, according to Ben Farral, study coordinator for UW-Madison.
Alzheimer’s is the only major disease where the number of cases are increasing annually, Farral noted. Current estimates state that 100,000 people in Wisconsin are living with Alzheimer’s and that number will increase to 130,000 by 2025.
The study is seeking adults ages 65 to 85 with normal memory and thinking abilities who can participate in the clinical trials through UW-Madison.
The study has specific eligibility requirements including that participants must have a study partner who has at least weekly contact with them who can answer questions once a year.
Study participants must be willing and able to receive monthly IV infusions of the investigational treatment or placebo for 36 months, and must be willing and able to participate in all required procedures for the duration of the study.
Study participants also must be willing to have their health monitored throughout the study using assessments such as memory and thinking tests, ECGs (looking at the heart), PET scans (a way to look for plaques thought to be associated with Alzheimer’s disease) MRI scans (takes a picture of the brain) and blood and urine tests.
For further information about the clinical trials at UW-Madison, contact Farral, the UW-Madison study coordinator, at (608)256-1901 ext. 11640.
To watch a video about the study and learn more about it, go to: http://a4study.org/